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CERTOLIZUMAB PEGOL
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DeCS
Descriptor
English
:
Certolizumab Pegol
Descriptor
Spanish
:
Certolizumab Pegol
Descriptor
Portuguese
:
Certolizumab Pegol
Tree Number:
D05.750.741.125
D12.644.541.500.650.250
D12.776.124.486.485.114.224.060.500
D12.776.124.486.485.680.650.250
D12.776.124.790.651.114.224.060.500
D12.776.124.790.651.680.650.250
D12.776.377.715.548.114.224.200.500
D12.776.377.715.548.680.650.250
D25.720.741.125
J01.637.051.720.741.125
Definition
English
:
A polyethylene-glycolated Fab' fragment of TUMOR
NECROSIS
FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and
IL-1 BETA
and is used to treat
RHEUMATOID ARTHRITIS
and PSORIATIC
ARTHRITIS.
History Note
English
:
2016 (2003)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
55953
Unique Identifier:
D000068582
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS